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A restrospective Drug Use Evaluation(DUE) study was conducted by reviewing medical records of 38 patients, who were given vancomycin during their hospitalization period at Kangnam St. Mary´s hospital, from 1 Oct 1997 to 31 November 1997. The criteria was midified from the criteria on vancomycin established by American society of Health-System Pharmacists(ASHP). As a result, 27 cases(71.1%) were met with the criteria for the justification of use. In 33 cases(86.8%), blood culture tests were performed within 48 hours before the initial doses. In 34 cases(89.5%), serum creatinine tests were conducted within 48 hours before the initial doses. In 22 cases(57.9%), fever peaks decreased at least 1 degree within 3 days after the initial dose and in 22 cases(57.9%), WBC values were in normal range after treatment. According to the study, inappropriate use of vancomycin was up to 28.9%. considering that vancomycin is categorized into one of restricted antibiotics, which can be used with an approval of infection specialist in the hospital, a more thorough control on use of vancomycin is required. Moreover, renal test should be carried out periodically before and during the use of vancomycin to prevent, if any, adverse reactions.
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